Article
Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus.
Journal of virology - 1 Oct 2015
Martín Verónica, Mavian Carla, López Bueno Alberto, de Molina Antonio, Díaz Eduardo, Andrés Germán, Alcami Antonio, Alejo Alí
Abstract excerpt
Amphibian-like ranaviruses include pathogens of fish, amphibians, and reptiles that have recently evolved from a fish-infecting ancestor. The molecular determinants of host range and virulence in this group are largely unknown, and currently fish infection models are lacking. We show that European sheatfish virus (ESV) can productively infect zebrafish, causing a lethal pathology, and describe a method for the...
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