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Development of the reverse genetics system for viral hemorrhagic septicemia virus genotype IVa and its application in antiviral compound screening.

Virologica Sinica - 1 Feb 2026

Huang Hao, Lu Xiaobing, Hong Tianlai, Chen Yihong, Yi Meisheng, Jia Kuntong

Abstract excerpt

Viral hemorrhagic septicemia virus (VHSV) is a major pathogen affecting freshwater and marine fish species, posing a significant threat to global aquaculture. Reverse genetics systems are essential for studying viral replication, and host interactions, as well as developing vaccines and therapeutics. In this study, we developed a reverse genetics platform for VHSVLB2018 strain, a genetically distinct VHSV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41461367
DOI: 10.1016/j.virs.2025.12.010
PMCID: PMC13007303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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