High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum

Abstract excerpt

Phage display is a prominent screening technique with a multitude of applications including therapeutic antibody development and mapping of antigen epitopes. In this study, phages were selected based on their interaction with patient serum and exhaustively characterised by high-throughput sequencing. A bioinformatics approach was developed in order to identify peptide motifs of interest based on clustering and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophages and microbial interactions
• Share to Monoclonal and Polyclonal Antibodies Research
• Share to Transgenic Plants and Applications