Article
Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges.
Pharmacogenomics - 1 Jan 2015
Hudson Andrew M, Wirth Christopher, Stephenson Natalie L, Fawdar Shameem, Brognard John, Miller Crispin J
Abstract excerpt
Lung cancer is the commonest cause of cancer death in the world and carries a poor prognosis for most patients. While precision targeting of mutated proteins has given some successes for never- and light-smoking patients, there are no proven targeted therapies for the majority of smokers with the disease. Despite sequencing hundreds of lung cancers, known driver mutations are lacking for a majority of tumors....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.