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Article

A novel mutation in the TMC1 gene causes non-syndromic hearing loss in a Moroccan family.

Gene - 10 Dec 2015

Bakhchane Amina, Charoute Hicham, Nahili Halima, Roky Rachida, Rouba Hassan, Charif Majida, Lenaers Guy, Barakat Abdelhamid

Abstract excerpt

Autosomal recessive non-syndromic hearing loss (ARNSHL) is one of the most common genetic diseases in human and is subject to important genetic heterogeneity, rendering molecular diagnosis difficult. Whole-exome sequencing is thus a powerful strategy for this purpose. After excluding GJB2 mutation and other common mutations associated with hearing loss in Morocco, whole-exome sequencing was performed to study the...

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Source

Identifiers

PMID: 26226225
DOI: 10.1016/j.gene.2015.07.075

Genes

TMC1
GJB2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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