Article
Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2016
Adams Hieab H H, Verlinden Vincentius J A, Callisaya Michele L, van Duijn Cornelia M, Hofman Albert, Thomson Russell, Uitterlinden André G, Vernooij Meike W, van der Geest Jos N, Srikanth Velandai, Ikram M Arfan
Abstract excerpt
Human gait is a complex neurological and musculoskeletal function, of which the genetic basis remains largely unknown. To determine the influence of common genetic variants on gait parameters, we studied 2,946 participants of the Rotterdam Study, a population-based cohort of unrelated elderly individuals. We assessed 30 gait parameters using an electronic walkway, which yielded seven independent gait domains...
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