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Article

Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2015

Sghaier Ikram, Mouelhi Leila, Gazouani Ezzedine, Morel Virginie, Besma Yacoubi Loueslati, Brochot Etienne

Abstract excerpt

BACKGROUND: Despite considerable progress in the treatment of chronic hepatitis C, many countries do not have access to these new treatments. OBJECTIVES: Predictive markers of response to treatment are therefore necessary before initiating with historical combination therapy (PEG-IFN+ribavirin) for these populations. STUDY DESIGN: We therefore evaluated the influence of IL28B polymorphisms on treatment response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26209404
DOI: 10.1016/j.jcv.2015.06.102

Genes

ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population.PMID 26209404Read ↗

Roles of ITPA and IL28B genotypes in chronic hepatitis C patients treated with peginterferon plus ribavirin.Semantic proximity Read ↗

Role of ITPA and IL28B variants in the management of chronic hepatitis C treatment.Semantic proximity Read ↗

ITPA genetic variants influence efficacy of PEG-IFN/RBV therapy in older patients infected with HCV genotype 1 and favourable IL28B type.Semantic proximity Read ↗

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Genome-wide association of IL-28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C in a Tunisian population.Semantic proximity Read ↗

Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C.Semantic proximity Read ↗

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