Article
Identifying genomic changes associated with insecticide resistance in the dengue mosquito Aedes aegypti by deep targeted sequencing.
Genome research - 1 Sept 2015
Faucon Frederic, Dusfour Isabelle, Gaude Thierry, Navratil Vincent, Boyer Frederic, Chandre Fabrice, Sirisopa Patcharawan, Thanispong Kanutcharee, Juntarajumnong Waraporn, Poupardin Rodolphe, Chareonviriyaphap Theeraphap, Girod Romain, Corbel Vincent, Reynaud Stephane, David Jean-Philippe
Abstract excerpt
The capacity of mosquitoes to resist insecticides threatens the control of diseases such as dengue and malaria. Until alternative control tools are implemented, characterizing resistance mechanisms is crucial for managing resistance in natural populations. Insecticide biodegradation by detoxification enzymes is a common resistance mechanism; however, the genomic changes underlying this mechanism have rarely been...
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