Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A multi-omic meta-analysis reveals novel mechanisms of insecticide resistance in malaria vectors

23 May 2025

Abstract excerpt

Malaria control faces challenges from widespread insecticide resistance in major Anopheles species. This study, employing a cross-species approach, integrates RNA-Sequencing, whole-genome sequencing, and microarray data to elucidate drivers of insecticide resistance in Anopheles gambiae complex and An. funestus. Here we show an inverse relationship between genetic diversity and gene expression, with highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Invertebrate Immune Response Mechanisms
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40410509
DOI: 10.1038/s42003-025-08221-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A multi-omic meta-analysis reveals novel mechanisms of insecticide resistance in malaria vectorsPMID 40410509Read ↗

Transcriptomic meta-signatures identified in Anopheles gambiae populations reveal previously undetected insecticide resistance mechanismsSemantic proximity Read ↗

Identifying genomic changes associated with insecticide resistance in the dengue mosquito Aedes aegypti by deep targeted sequencing.Semantic proximity Read ↗

Multi-omics analysis identifies loci associated with pyrethroid resistance across sister species in the <i>Anopheles gambiae</i> species complexSemantic proximity Read ↗

A whole transcriptomic approach reveals novel mechanisms of organophosphate and pyrethroid resistance in <i>Anopheles arabiensis</i> from EthiopiaSemantic proximity Read ↗

RNA‐Seq‐Pop : Exploiting the sequence in RNA sequencing—A Snakemake workflow reveals patterns of insecticide resistance in the malaria vector Anopheles gambiaeSemantic proximity Read ↗

Key gene modules and hub genes associated with pyrethroid and organophosphate resistance in Anopheles mosquitoes: a systems biology approachSemantic proximity Read ↗

Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele-specific expression.Semantic proximity Read ↗

Transcriptomic profiling reveals multiple mechanisms of insecticide resistance in <i>Aedes aegypti</i> from AngolaSemantic proximity Read ↗

Comparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencing.Semantic proximity Read ↗

Multi-omics analysis identifies loci associated with pyrethroid resistance across sister species in the Anopheles gambiae species complex.Semantic proximity Read ↗

Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across AfricaSemantic proximity Read ↗

Contrasting patterns of gene expression indicate differing pyrethroid resistance mechanisms across the range of the New World malaria vector Anopheles albimanusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.