Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole exome sequencing in extended families with autism spectrum disorder implicates four candidate genes.

Human genetics - 1 Oct 2015

Chapman Nicola H, Nato Alejandro Q, Bernier Raphael, Ankenman Katy, Sohi Harkirat, Munson Jeff, Patowary Ashok, Archer Marilyn, Blue Elizabeth M, Webb Sara Jane, Coon Hilary, Raskind Wendy H, Brkanac Zoran, Wijsman Ellen M

Abstract excerpt

Autism spectrum disorders (ASDs) are a group of neurodevelopmental disorders, characterized by impairment in communication and social interactions, and by repetitive behaviors. ASDs are highly heritable, and estimates of the number of risk loci range from hundreds to >1000. We considered 7 extended families (size 12-47 individuals), each with ≥3 individuals affected by ASD. All individuals were genotyped with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to Exome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eye Proteins

Share to Genes, Dominant

Share to Linkage Disequilibrium

Share to Membrane Proteins

Share to Phosphotransferases (Phosphate Group Acceptor)

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26204995
DOI: 10.1007/s00439-015-1585-y
PMCID: PMC4578871

Genes

FEZF1
SAMD11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole exome sequencing in extended families with autism spectrum disorder implicates four candidate genes.PMID 26204995Read ↗

Exome sequencing of 457 autism families recruited online provides evidence for novel ASD genesSemantic proximity Read ↗

Haplotype structure enables prioritization of common markers and candidate genes in autism spectrum disorder.Semantic proximity Read ↗

New Candidates for Autism/Intellectual Disability Identified by Whole-Exome Sequencing.Semantic proximity Read ↗

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autismSemantic proximity Read ↗

Whole exome sequencing reveals inherited and de novo variants in autism spectrum disorder: a trio study from Saudi families.Semantic proximity Read ↗

Using extended pedigrees to identify novel autism spectrum disorder (ASD) candidate genes.Semantic proximity Read ↗

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.Semantic proximity Read ↗

Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.Semantic proximity Read ↗

The Importance of Large-Scale Genomic Studies to Unravel Genetic Risk Factors for Autism.Semantic proximity Read ↗

Unveiling Hidden Genetic Architectures: Molecular Diagnostic Yield of Whole Exome Sequencing in 50 Children With Autism Spectrum Disorder Negative for Copy Number Variations.Semantic proximity Read ↗

Autism spectrum disorder trios from consanguineous populations are enriched for rare homozygous variants, identifying 32 new candidate genes.Semantic proximity Read ↗

Whole exome sequencing in females with autism implicates novel and candidate genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.