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Article

New Candidates for Autism/Intellectual Disability Identified by Whole-Exome Sequencing.

International journal of molecular sciences - 14 Dec 2021

Bruno Lucia Pia, Doddato Gabriella, Valentino Floriana, Baldassarri Margherita, Tita Rossella, Fallerini Chiara, Bruttini Mirella, Lo Rizzo Caterina, Mencarelli Maria Antonietta, Mari Francesca, Pinto Anna Maria, Fava Francesca, Fabbiani Alessandra, Lamacchia Vittoria, Carrer Anna, Caputo Valentina, Granata Stefania, Benetti Elisa, Zguro Kristina, Furini Simone, Renieri Alessandra, Ariani Francesca

Abstract excerpt

Intellectual disability (ID) is characterized by impairments in the cognitive processes and in the tasks of daily life. It encompasses a clinically and genetically heterogeneous group of neurodevelopmental disorders often associated with autism spectrum disorder (ASD). Social and communication abilities are strongly compromised in ASD. The prevalence of ID/ASD is 1-3%, and approximately 30% of the patients remain...

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Identifiers

PMID: 34948243
DOI: 10.3390/ijms222413439
PMCID: PMC8707363

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