Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progressive retinal atrophy in Shetland sheepdog is associated with a mutation in the CNGA1 gene.

Animal genetics - 1 Oct 2015

Wiik A C, Ropstad E O, Ekesten B, Karlstam L, Wade C M, Lingaas F

Abstract excerpt

Progressive retinal atrophy (PRA) is the collective name of a class of hereditary retinal dystrophies in the dog and is often described as the equivalent of retinitis pigmentosa in humans. PRA is characterized by visual impairment due to degeneration of the photoreceptors in the retina, usually leading to blindness. PRA has been reported in dogs from more than 100 breeds and can be genetically heterogeneous both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Cyclic Nucleotide-Gated Cation Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Frameshift Mutation

Share to Retinal Degeneration

Share to Scandinavian and Nordic Countries

Share to Sequence Deletion

Source

Identifiers

PMID: 26202106
DOI: 10.1111/age.12323

Genes

CNGA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progressive retinal atrophy in Shetland sheepdog is associated with a mutation in the CNGA1 gene.PMID 26202106Read ↗

Elucidating the genetic basis of canine progressive retinal atrophies in several breeds of dogSemantic proximity Read ↗

Late-onset progressive retinal atrophy in the Gordon and Irish Setter breeds is associated with a frameshift mutation in C2orf71.Semantic proximity Read ↗

A CNGB1 Frameshift Mutation in Papillon and Phalène Dogs with Progressive Retinal AtrophySemantic proximity Read ↗

A Missense Variant in the Bardet-Biedl Syndrome 2 Gene (BBS2) Leads to a Novel Syndromic Retinal Degeneration in the Shetland Sheepdog.Semantic proximity Read ↗

A Frameshift Mutation in Golden Retriever Dogs with Progressive Retinal Atrophy Endorses SLC4A3 as a Candidate Gene for Human Retinal DegenerationsSemantic proximity Read ↗

Genetic screening for PRA-associated mutations in multiple dog breeds shows that PRA is heterogeneous within and between breeds.Semantic proximity Read ↗

An Intronic SINE insertion in FAM161A that causes exon-skipping is associated with progressive retinal atrophy in Tibetan Spaniels and Tibetan Terriers.Semantic proximity Read ↗

A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs.Semantic proximity Read ↗

Identification of the mutation causing progressive retinal atrophy in Old Danish Pointing Dog.Semantic proximity Read ↗

Identification of putative SNPs in progressive retinal atrophy affected Canis lupus familiaris using exome sequencing.Semantic proximity Read ↗

Gene Panel Screening Across Canine Eye Disorders Highlights Genetic Heterogeneity and the Need for Molecular DiscoveriesSemantic proximity Read ↗

Preliminary characterization of a novel form of progressive retinal atrophy in the German Spitz dog associated with a frameshift mutation in GUCY2D.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.