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Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

7 Jul 2015

Abstract excerpt

Drug resistance prevents the successful treatment of HIV-positive individuals by decreasing viral sensitivity to a drug or a class of drugs. In addition to transmitted resistant viruses, treatment-naïve individuals can be confronted with the problem of drug resistance through de novo emergence of such variants. Resistant viruses have been reported for every antiretroviral drug tested so far, including the...

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PMID: 26198244
DOI: 10.3390/v7072790

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