Article
Analysis of Conserved Glutamate and Aspartate Residues in Drosophila Rhodopsin 1 and Their Influence on Spectral Tuning.
The Journal of biological chemistry - 4 Sept 2015
Zheng Lijun, Farrell David M, Fulton Ruth M, Bagg Eve E, Salcedo Ernesto, Manino Meridee, Britt Steven G
Abstract excerpt
The molecular mechanisms that regulate invertebrate visual pigment absorption are poorly understood. Studies of amphioxus Go-opsin have demonstrated that Glu-181 functions as the counterion in this pigment. This finding has led to the proposal that Glu-181 may function as the counterion in other invertebrate visual pigments as well. Here we describe a series of mutagenesis experiments to test this hypothesis and...
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