Article
An Increased Risk of Second Malignant Neoplasms After Rhabdomyosarcoma: Population-Based Evidence for a Cancer Predisposition Syndrome?
Pediatric blood & cancer - 1 Feb 2016
Archer Natasha M, Amorim Renata Parada, Naves Rafaela, Hettmer Simone, Diller Lisa R, Ribeiro Karina Braga, Rodriguez-Galindo Carlos
Abstract excerpt
BACKGROUND: Rhabdomyosarcoma survivors have an increased risk of developing second malignant neoplasms (SMN); this risk is traditionally attributed to the effects of multidisciplinary management required for cure. However, the impact of constitutional predisposition has not been properly analyzed. METHODS: We analyzed the risk of SMN among 1,151 children diagnosed with rhabdomyosarcoma and reported to the...
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