Article
Tumor necrosis factor-α and interleukin-1β gene polymorphisms and risk of brain abscess in North Indian population.
Cytokine - 1 Sept 2015
Mishra Priyanka, Prasad Kashi Nath, Singh Kamini, Bajpai Anamika, Sahu Rabi Narayan, Ojha Bal Krishna
Abstract excerpt
OBJECTIVE: Brain abscess develops in response to a parenchymal infection with pyogenic bacteria. Tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are the most crucial pro-inflammatory cytokines with both beneficial and destructive properties for the central nervous system. The present study evaluated the association of specific alleles/genotypes of TNF-α and IL-1β with brain abscess. MATERIAL AND...
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