Article
Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2016
Aebi Marcel, van Donkelaar Marjolein M J, Poelmans Geert, Buitelaar Jan K, Sonuga-Barke Edmund J S, Stringaris Argyris, Consortium Image, Faraone Stephen V, Franke Barbara, Steinhausen Hans-Christoph, van Hulzen Kimm J E
Abstract excerpt
Oppositional defiant disorder (ODD) is a frequent psychiatric disorder seen in children and adolescents with attention-deficit-hyperactivity disorder (ADHD). ODD is also a common antecedent to both affective disorders and aggressive behaviors. Although the heritability of ODD has been estimated to be around 0.60, there has been little research into the molecular genetics of ODD. The present study examined the...
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