Article
Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi.
PloS one - 1 Jan 2015
Glynn Judith R, Guerra-Assunção José Afonso, Houben Rein M G J, Sichali Lifted, Mzembe Themba, Mwaungulu Lorrain K, Mwaungulu J Nimrod, McNerney Ruth, Khan Palwasha, Parkhill Julian, Crampin Amelia C, Clark Taane G
Abstract excerpt
BACKGROUND: The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and prior contacts allows transmission to be confirmed or excluded. METHODS: In Karonga District, Malawi, all tuberculosis patients are asked about prior contact with others with tuberculosis. All available strains from culture-positive patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.