Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protecting the normal in order to better kill the cancer.

Cancer medicine - 1 Sept 2015

Liu Bingya, Ezeogu Lewis, Zellmer Lucas, Yu Baofa, Xu Ningzhi, Joshua Liao Dezhong

Abstract excerpt

Chemotherapy is the only option for oncologists when a cancer has widely spread to different body sites. However, almost all currently available chemotherapeutic drugs will eventually encounter resistance after their initial positive effect, mainly because cancer cells develop genetic alterations, collectively coined herein as mutations, to adapt to the therapy. Some patients may still respond to a second chemo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Drug Resistance, Neoplasm
Share to Molecular Targeted Therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Share to Prognosis

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 26177855
DOI: 10.1002/cam4.488
PMCID: PMC4567024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protecting the normal in order to better kill the cancer.PMID 26177855Read ↗

Drug Resistance in Cancers: A Free Pass for BullyingSemantic proximity Read ↗

Identifying and Targeting the Cause of Cancer is Needed to Cure CancerSemantic proximity Read ↗

Cancer - A devastating disease, but also an eye-opener and window into the deep mysteries of life and its origins.Semantic proximity Read ↗

Drug tolerant persister cell plasticity in cancer: a revolutionary strategy for more effective anticancer therapiesSemantic proximity Read ↗

Cancer drug-tolerant persister cells: from biological questions to clinical opportunitiesSemantic proximity Read ↗

Mechanism of Drug Tolerant Persister Cancer Cells: The Landscape and Clinical Implication for TherapySemantic proximity Read ↗

Natural resistance to cancer: A window of hope.Semantic proximity Read ↗

Cellular Response to an Act of Surviving Drives Tumor Evolution and Tumor HeterogeneitySemantic proximity Read ↗

[A reductionnist approach of cancer].Semantic proximity Read ↗

[Achieving self-destruction of cancer cells].Semantic proximity Read ↗

Molecular Mechanisms for Targeting Metastatic Cancer Cells and to Overcome or Prevent Chemotherapy ResistanceSemantic proximity Read ↗

How Cancer Could be Cured by 2015Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.