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Article

Association of Angiotensin-Converting Enzyme (ACE) Gene Polymorphism with Inflammation and Cellular Cytotoxicity in Vitiligo Patients.

PloS one - 1 Jan 2015

Rashed Laila, Abdel Hay Rania, Mahmoud Rania, Hasan Nermeen, Zahra Amr, Fayez Salwa

Abstract excerpt

BACKGROUND: Vitiligo is a disorder with profound heterogeneity in its aetio-pathophysiology. Angiotensin converting enzyme (ACE) plays an important role in the physiology of the vasculature, blood pressure and inflammation. An insertion/deletion (I/D) polymorphism of the ACE gene was reported be associated with the development of vitiligo. OBJECTIVE: Our aim was to evaluate the ACE I/D polymorphism in vitiligo...

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Source

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Identifiers

PMID: 26177100
DOI: 10.1371/journal.pone.0132915
PMCID: PMC4503778

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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