Article
The angiotensin-converting enzyme gene insertion/deletion polymorphism in Indian patients with vitiligo: a case-control study and meta-analysis.
The British journal of dermatology - 1 Jun 2013
Patwardhan M, Pradhan V, Taylor L H, Thakkar V, Kharkar V, Khopkar U, Ghosh K, Gawkrodger D J, Teare M D, Weetman A P, Kemp E H
Abstract excerpt
BACKGROUND: Vitiligo is a common, acquired, idiopathic depigmenting skin disorder. Although the exact pathogenesis remains unknown, genetic susceptibility and autoimmune responses play a role in vitiligo development. Previous studies have suggested that the D allele of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated with vitiligo in Indians and Koreans....
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