Article
Genome-wide expression and methylation profiles reveal candidate genes and biological processes underlying synovial inflammatory tissue of patients with osteoarthritis.
International journal of rheumatic diseases - 1 Sept 2015
Yang Jianxun, Wang Ning
Abstract excerpt
AIM: The aim of the study was to identify osteoarthritis (OA)-related biological markers and processes. METHODS: The gene expression profile GSE46750 including 12 normal and 12 inflammatory synovial membrane samples, as well as the DNA methylation profile GSE43269, including 18 normal samples and 23 OA samples, were used. Differentially expressed genes (DEGs) and differentially methylated genes (DMGs) were...
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