Analysis of gene expression and methylation datasets identified ADAMTS9, FKBP5, and PFKBF3 as biomarkers for osteoarthritis

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a kind of chronic osteoarthropathy and degenerative joint disease. Epigenetic regulation in the gene expression dynamics has become increasingly important in OA. We performed a combined analysis of two types of microarray datasets (gene expression and DNA methylation) to identify methylation-based key biomarkers to provide a better understanding of molecular biological...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Osteoarthritis Treatment and Mechanisms
• Share to Phosphodiesterase function and regulation
• Share to Rheumatoid Arthritis Research and Therapies