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Article

The role of climate and out-of-Africa migration in the frequencies of risk alleles for 21 human diseases.

BMC genetics - 14 Jul 2015

Blair Lily M, Feldman Marcus W

Abstract excerpt

BACKGROUND: Demography and environmental adaptation can affect the global distribution of genetic variants and possibly the distribution of disease. Population heterozygosity of single nucleotide polymorphisms has been shown to decrease strongly with distance from Africa and this has been attributed to the effect of serial founding events during the migration of humans out of Africa. Additionally, population...

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Identifiers

PMID: 26170196
DOI: 10.1186/s12863-015-0239-3
PMCID: PMC4501093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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