Article
Genome-wide pathway analysis for diabetic nephropathy in type 1 diabetes.
Endocrine research - 1 Jan 2016
Lee Young Ho, Song Gwan Gyu
Abstract excerpt
OBJECTIVE: The aim of this study was to identify candidate single-nucleotide polymorphisms (SNPs) that might play a role in susceptibility to diabetic nephropathy (DN) in type 1 diabetes, elucidate their potential mechanisms, and generate SNP-to-gene-to-pathway hypotheses. METHODS: A genome-wide association study (GWAS) dataset of DN in type 1 diabetes, which included 345,363 SNPs from a total of 1,705 samples...
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