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Functional Network Analysis Reveals Versatile MicroRNAs in Human Heart

1 Jan 2015

Abstract excerpt

BACKGROUND: Acting on many mRNAs allows the power of a single miRNA to modulate multiple pathophysiological phenotypes. One question is whether versatile miRNAs exist in the pathological scenarios of myocardial infarction (MI) and heart failure (HF). METHODS: A hypergeometric analysis, in combination with network-based functional analyses, was performed on the available human protein interaction and miRNA-gene...

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PMID: 26160134
DOI: 10.1159/000430324

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