Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systems Biology in Chronic Heart Failure—Identification of Potential miRNA Regulators

3 Dec 2022

Abstract excerpt

Heart failure (HF) is a complex disease entity with high clinical impact, poorly understood pathophysiology and scantly known miRNA-mediated epigenetic regulation. We have analysed miRNA patterns in patients with chronic HF (cHF) and a sex- and age-matched reference group and pursued an in silico system biology analysis to discern pathways involved in cHF pathophysiology. Twenty-eight miRNAs were identified in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Fibrosis and Remodeling
Share to GDF15 and Related Biomarkers
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36499552
DOI: 10.3390/ijms232315226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systems Biology in Chronic Heart Failure—Identification of Potential miRNA RegulatorsPMID 36499552Read ↗

Integrative System Biology Analyses Identify Seven Micrornas to Predict Heart FailureSemantic proximity Read ↗

Regulatory network analysis based on integrated miRNA-TF reveals key genes in heart failureSemantic proximity Read ↗

Functional Role of MiRNA in Cardiac Resynchronization TherapySemantic proximity Read ↗

Unveiling miRNA Biomarkers for Hypertrophic Cardiomyopathy through Integrated Bioinformatics and Machine Learning AnalysisSemantic proximity Read ↗

MicroRNAs--regulators of signaling networks in dilated cardiomyopathy.Semantic proximity Read ↗

MiRNA-Regulated Pathways for Hypertrophic Cardiomyopathy: Network-Based Approach to Insight into PathogenesisSemantic proximity Read ↗

Potential diagnostic value of circulating miRNAs in HFrEF and bioinformatics analysisSemantic proximity Read ↗

Myocardial microRNAs associated with reverse remodeling in human heart failureSemantic proximity Read ↗

Identification of microRNAs associated with heart failure with reduced ejection fractionSemantic proximity Read ↗

Integrated analysis of mRNA and microRNA expression profiles reveals differential transcriptome signature in ischaemic and dilated cardiomyopathy induced heart failureSemantic proximity Read ↗

Differential expression profiles of plasma exosomal microRNAs in dilated cardiomyopathy with chronic heart failureSemantic proximity Read ↗

Functional Network Analysis Reveals Versatile MicroRNAs in Human HeartSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.