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Article

Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume.

PloS one - 1 Jan 2015

Giri Ayush, Edwards Todd L, Motley Saundra S, Byerly Susan H, Fowke Jay H

Abstract excerpt

Prostate enlargement leading to clinical benign prostatic hyperplasia (BPH) is associated with metabolic dysregulation and obesity. The genetic basis of this association is unclear. Our objective was to evaluate whether single nucleotide polymorphisms (SNPs) previously associated with metabolic disorders are also associated with prostate volume (PV). Participants included 876 men referred for prostate biopsy and...

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Identifiers

PMID: 26158673
DOI: 10.1371/journal.pone.0132028
PMCID: PMC4497718

Genes

NRXN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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