Article
Muscle exercise in limb girdle muscular dystrophies: pitfall and advantages.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology - 1 May 2015
Siciliano Gabriele, Simoncini Costanza, Giannotti Stefano, Zampa Virna, Angelini Corrado, Ricci Giulia
Abstract excerpt
Different genetic mutations underlying distinct pathogenic mechanisms have been identified as cause of muscle fibers degeneration and strength loss in limb girdle muscular dystrophies (LGMD). As a consequence, exercise tolerance is affected in patients with LGMD, either as a direct consequence of the loss of muscle fibers or secondary to the sedentary lifestyle due to the motor impairment. It has been debated for...
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