Article
C. elegans SoxB genes are dispensable for embryonic neurogenesis but required for terminal differentiation of specific neuron types.
Development (Cambridge, England) - 15 Jul 2015
Vidal Berta, Santella Anthony, Serrano-Saiz Esther, Bao Zhirong, Chuang Chiou-Fen, Hobert Oliver
Abstract excerpt
Neurogenesis involves deeply conserved patterning molecules, such as the proneural basic helix-loop-helix transcription factors. Sox proteins and specifically members of the SoxB and SoxC groups are another class of conserved transcription factors with an important role in neuronal fate commitment and differentiation in various species. In this study, we examine the expression of all five Sox genes of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
