Borrelia burgdorferi RevA Significantly Affects Pathogenicity and Host Response in the Mouse Model of Lyme Disease

Abstract excerpt

The Lyme disease spirochete, Borrelia burgdorferi, expresses RevA and numerous outer surface lipoproteins during mammalian infection. As an adhesin that promotes bacterial interaction with fibronectin, RevA is poised to interact with the extracellular matrix of the host. To further define the role(s) of RevA during mammalian infection, we created a mutant that is unable to produce RevA. The mutant was still...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Vector-Borne Animal Diseases
• Share to Vector-borne infectious diseases
• Share to Viral Infections and Vectors