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Article

Distinct Protein Expression Profiles of Solid-Pseudopapillary Neoplasms of the Pancreas

7 Jul 2015

Abstract excerpt

Solid-pseudopapillary neoplasm (SPN) is an uncommon pancreatic tumor with mutation in CTNNB1 and distinct clinical and pathological features. We compared the proteomic profiles of SPN to mRNA expression. Pooled SPNs and pooled non-neoplastic pancreatic tissues were examined with high-resolution mass spectrometry. We identified 329 (150 up-regulated and 179 down-regulated) differentially expressed proteins in SPN....

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PMID: 26148796
DOI: 10.1021/acs.jproteome.5b00423

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