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Article

A novel homozygous variant in the dsp gene underlies the first case of non-syndromic form of alopecia.

Archives of dermatological research - 1 Nov 2015

Jan Abid, Basit Sulman, Wakil Salma M, Ramzan Khushnooda, Ahmad Wasim

Abstract excerpt

Autosomal recessive forms of hair loss (alopecia) disorders have previously been associated with variants in at least five different genes including hairless (HR), desmoglein-4 (DSG4), desmocollin-3 (DSC3), lipase-H (LIPH), and lysophosphatidic acid receptor 6 (LPAR6). Here, we report the first familial case of alopecia resulting from a novel homozygous variant in the DSP gene. Since previous reports indicated...

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Source

Identifiers

PMID: 26148547
DOI: 10.1007/s00403-015-1590-y

Genes

DSP
DSC3
DSG4
LIPH
LPAR6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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