Article
Intracellular siderophore but not extracellular siderophore is required for full virulence in Metarhizium robertsii.
Fungal genetics and biology : FG & B - 1 Sept 2015
Giuliano Garisto Donzelli Bruno, Gibson Donna M, Krasnoff Stuart B
Abstract excerpt
Efficient iron acquisition mechanisms are fundamental for microbial survival in the environment and for pathogen virulence within their hosts. M. robertsii produces two known iron-binding natural products: metachelins, which are used to scavenge extracellular iron, and ferricrocin, which is strictly intracellular. To study the contribution of siderophore-mediated iron uptake and storage to M. robertsii fitness,...
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