Article
Increased Cardiovascular and Metabolic Morbidity in Patients With 21-Hydroxylase Deficiency: A Swedish Population-Based National Cohort Study.
The Journal of clinical endocrinology and metabolism - 1 Sept 2015
Falhammar Henrik, Frisén Louise, Hirschberg Angelica Linden, Norrby Christina, Almqvist Catarina, Nordenskjöld Agneta, Nordenström Anna
Abstract excerpt
CONTEXT: Congenital adrenal hyperplasia (CAH) is lethal in its most severe forms if not treated with glucocorticoids. However, glucocorticoids may increase the risk of cardiovascular and metabolic morbidity. OBJECTIVE: This study aimed to study cardiovascular and metabolic morbidity in CAH. DESIGN, SETTING, AND PARTICIPANTS: Patients with CAH due to 21-hydroxylase deficiency (n = 588; >80% with known CYP21A2...
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