Congenital adrenal hyperplasia due to 21 hydroxylase deficiency: from birth to adulthood.

Abstract excerpt

The most frequent form of congenital adrenal hyperplasia (CAH) is steroid 21-hydroxylase deficiency, accounting for more than 90% of cases. Affected patients cannot synthesize cortisol efficiently. Thus the adrenal cortex is stimulated by corticotropin (ACTH) and overproduces cortisol precursors. Some precursors are diverted to sex hormone biosynthesis, causing signs of androgen excess including ambiguous...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adolescent
• Share to Adrenal Hyperplasia, Congenital
• Share to Child