Article
BRAFV600E Mutation in Melanotic Neuroectodermal Tumor of Infancy: Toward Personalized Medicine?
Pediatrics - 1 Jul 2015
Gomes Carolina C, Diniz Marina G, de Menezes Grazielle Helena F, Castro Wagner H, Gomez Ricardo S
Abstract excerpt
The melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm that primarily affects the maxilla of infants during their first year of life. Complete resection is the conventional treatment and recurrence rates vary from 10% to 60%. The recurrent tumors grow more aggressively and can invade other anatomic structures, such as the nasal cavity, the orbit, and the skull base. The aggressive behavior of...
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