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Article

Distinct phenotypic changes between the superficial and deep component of giant congenital melanocytic naevi: a rationale for curettage.

The British journal of dermatology - 1 Mar 2006

De Raeve L E, Claes A, Ruiter D J, van Muijen G N P, Roseeuw D, van Kempen L C L T

Abstract excerpt

BACKGROUND: Giant congenital melanocytic naevi (GCMN) convey a 14-fold increased melanoma risk. In contrast, medium congenital melanocytic naevi (MCMN) are rarely associated with malignant transformation. Management of patients with GCMN is challenging and there is no consensus on the most appropriate strategy for treating these patients. OBJECTIVES: To provide a rationale for performing curettage of GCMN in the...

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Identifiers

PMID: 16445780
DOI: 10.1111/j.1365-2133.2005.07055.x

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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