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Article

Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system.

Pathology, research and practice - 1 Aug 2015

Michl Marlies, Heinemann Volker, Jung Andreas, Engel Jutta, Kirchner Thomas, Neumann Jens

Abstract excerpt

INTRODUCTION: In colorectal cancer (CRC), metastatic spread is supposed to be mainly driven by tumor cells with stem cell features. Only about 1% of all CRC patients develop metastasis to the central nervous system (CNS). The present study intended to analyze the correlation between the expression of cancer stem cell markers and patterns of liver or CNS metastases. MATERIAL AND METHODS: Immunohistochemistry for...

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Source

Identifiers

PMID: 26092596
DOI: 10.1016/j.prp.2015.05.006

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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