Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci.

doi:10.1007/s12026-015-8671-z

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Article

Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci.

Immunologic research - 1 Feb 2016

Nexø Bjørn A, Villesen Palle, Nissen Kari K, Lindegaard Hanne M, Rossing Peter, Petersen Thor, Tarnow Lise, Hansen Bettina, Lorenzen Tove, Hørslev-Petersen Kim, Jensen Sara B, Bahrami Shervin, Lajer Maria, Schmidt Kathrine L M, Parving Hans-Henrik, Junker Peter, Laska Magdalena J

Abstract excerpt

Autoimmune diseases encompass a plethora of conditions in which the immune system attacks its own tissue, identifying them as foreign. Multiple factors are thought to contribute to the development of immune response to self, including differences in genotypes, hormonal milieu, and environmental factors. Viruses including human endogenous retroviruses have long been linked to the occurrence of autoimmunity, but...

Topics

Arthritis, Rheumatoid
Autoimmunity
Diabetes Mellitus, Type 1
Endogenous Retroviruses
Female
Gene Regulatory Networks
Genetic Association Studies
Genetic Loci
Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Humans

Immunity, Innate

Male

Multiple Sclerosis

Polymorphism, Single Nucleotide

Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26091722
DOI: 10.1007/s12026-015-8671-z
PMCID: PMC4726719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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