Article
[Experience with the use of gefitinib in patients with inoperable non-squamous cell lung cancer with activating EGFR mutations].
Voprosy onkologii - 1 Jan 2015
Moiseenko V M, Chubenko V A, Moiseenko F V, Ivantsov A O, Kramchaninov M M, Imyanitov E N
Abstract excerpt
Discovery of activating EGFR mutations led to dramatic modification of treatment schemes for nonsquamous lung cancer. 70 patients with activating EGFR mutations were treated by gefitinib being either a part of prospective phase II trial (n = 25) or, subsequently, subjected to routine clinical management (n = 45). Objective response rate approached to 32.7%. Median time to disease progression was 14 months, and...
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