Article
Rapid Immunochromatographic Detection of Serum Anti-α-Galactosidase A Antibodies in Fabry Patients after Enzyme Replacement Therapy.
PloS one - 1 Jan 2015
Nakano Sachie, Tsukimura Takahiro, Togawa Tadayasu, Ohashi Toya, Kobayashi Masahisa, Takayama Katsuyoshi, Kobayashi Yukuharu, Abiko Hiroshi, Satou Masatsugu, Nakahata Tohru, Warnock David G, Sakuraba Hitoshi, Shibasaki Futoshi
Abstract excerpt
We developed an immunochromatography-based assay for detecting antibodies against recombinant α-galactosidase A proteins in serum. The evaluation of 29 serum samples from Fabry patients, who had received enzyme replacement therapy with agalsidase alpha and/or agalsidase beta, was performed by means of this assay method, and the results clearly revealed that the patients exhibited the same level of antibodies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.