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Article

Generation and characterization of nucleic acid aptamers targeting the capsid P domain of a human norovirus GII.4 strain

14 Jun 2015

Abstract excerpt

Human noroviruses (NoV) are the leading cause of acute viral gastroenteritis worldwide. Significant antigenic diversity of NoV strains has limited the availability of broadly reactive ligands for design of detection assays. The purpose of this work was to produce and characterize single stranded (ss)DNA aptamers with binding specificity to human NoV using an easily produced NoV target-the P domain protein....

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PMID: 26080079
DOI: 10.1016/j.jbiotec.2015.06.389

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