Article
Significant association between rare IPO11-HTR1A variants and attention deficit hyperactivity disorder in Caucasians.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2015
Zuo Lingjun, Saba Laura, Lin Xiandong, Tan Yunlong, Wang Kesheng, Krystal John H, Tabakoff Boris, Luo Xingguang
Abstract excerpt
We comprehensively examined the rare variants in the IPO11-HTR1A region to explore their roles in neuropsychiatric disorders. Five hundred seventy-three to 1,181 rare SNPs in subjects of European descent and 1,234-2,529 SNPs in subjects of African descent (0 < minor allele frequency (MAF) < 0.05) were analyzed in a total of 49,268 subjects in 21 independent cohorts with 11 different neuropsychiatric disorders....
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