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Article

A knowledgebase resource for interleukin-17 family mediated signaling

15 Jun 2015

Abstract excerpt

Interleukin-17 (IL-17) belongs to a relatively new family of cytokines that has garnered attention as the signature cytokine of Th17 cells. This cytokine family consists of 6 ligands, which bind to 5 receptor subtypes and induce downstream signaling. Although the receptors are ubiquitously expressed, cellular responses to ligands vary across tissues. The cytokine family is associated with various autoimmune...

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PMID: 26077014
DOI: 10.1007/s12079-015-0297-3

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