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Article

Lhx8 regulates primordial follicle activation and postnatal folliculogenesis

15 Jun 2015

Abstract excerpt

BACKGROUND: The early stages of ovarian follicle formation-beginning with the breakdown of germ cell cysts and continuing with the formation of primordial follicles and transition to primary and secondary follicles-are critical in determining reproductive life span and fertility. Previously, we discovered that global knockouts of germ cell-specific transcriptional co-regulators Sohlh1, Sohlh2, Lhx8, and Nobox,...

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PMID: 26076587
DOI: 10.1186/s12915-015-0151-3

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