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Article

Oxidative proteome alterations during skeletal muscle ageing

5 Jun 2015

Abstract excerpt

Sarcopenia corresponds to the degenerative loss of skeletal muscle mass, quality, and strength associated with ageing and leads to a progressive impairment of mobility and quality of life. However, the cellular and molecular mechanisms involved in this process are not completely understood. A hallmark of cellular and tissular ageing is the accumulation of oxidatively modified (carbonylated) proteins, leading to a...

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PMID: 26073261
DOI: 10.1016/j.redox.2015.05.006

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