Article
In silico phenotyping via co-training for improved phenotype prediction from genotype.
Bioinformatics (Oxford, England) - 15 Jun 2015
Roqueiro Damian, Witteveen Menno J, Anttila Verneri, Terwindt Gisela M, van den Maagdenberg Arn M J M, Borgwardt Karsten
Abstract excerpt
MOTIVATION: Predicting disease phenotypes from genotypes is a key challenge in medical applications in the postgenomic era. Large training datasets of patients that have been both genotyped and phenotyped are the key requisite when aiming for high prediction accuracy. With current genotyping projects producing genetic data for hundreds of thousands of patients, large-scale phenotyping has become the bottleneck in...
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