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Generating and Analyzing Germ‐Free Mice

1 Dec 2012

Abstract excerpt

The normal gut microbiota has evoked many investigators' interest over the years and the pioneering work of James Reyniers in the 1920s generated the first germ-free guinea pigs. Comparing the physiology between germ-free and conventionally raised animals has provided invaluable insights on how the gut microbiota affect host biology. Today we know that the gut microbiota modulate the immune system, epithelial...

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PMID: 26069017
DOI: 10.1002/9780470942390.mo120064

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