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Gnotobiotic Rodents: An In Vivo Model for the Study of Microbe–Microbe Interactions

30 Mar 2016

Abstract excerpt

Germ-free rodents have no microorganisms living in or on them, allowing researchers to specifically control an animal's microbiota through the direct inoculation of bacteria of interest. This strategy has been widely used to decipher host-microbe interactions as well as the role of microorganisms in both (i) the development and function of the gut barrier (mainly the intestinal epithelium) and (ii) homeostasis...

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PMID: 27065973
DOI: 10.3389/fmicb.2016.00409

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